Focus on the cetirizine use in clinical practice: a reappraisal 30 years later

  • Angelo C. Corsico Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy.
  • Salvatore Leonardi Department of Clinical and Experimental Medicine, University of Catania, Catania,, Italy.
  • Amelia Licari Department of Pediatrics, Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
  • Gianluigi Marseglia Department of Pediatrics, Foundation IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
  • Michele Miraglia del Giudice Department of Woman, Child and of General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, Naples, Italy.
  • Diego G. Peroni U.O. Pediatria, Azienda Ospedaliero-Universitaria Pisana, Scuola di Specializzazione in Pediatria, University of Pisa, Pisa, Italy.
  • Carmelo Salpietro Department of Pediatrics, Unit of Pediatric Genetics and Immunology, University of Messina, Messina, Italy.
  • Giorgio Ciprandi | gio.cip@libero.it Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy., Italy. http://orcid.org/0000-0001-7016-8421

Abstract

Antihistamines are currently one of the most commonly administered categories of drugs. They are used to treat symptoms that are secondary to histamine release, which is typical of certain allergic conditions, including rhinitis, conjunctivitis, asthma, urticaria, and anaphylaxis. Cetirizine belongs to the second-generation family, so, it is very selective for peripheral H1 receptors, is potent and quickly relieves symptoms, exerts additional anti-allergic/antiinflammatory effects, and is usually well-tolerated. It has been marketed 30 years ago. In these years, a remarkable body of evidence has been built. The current review provides a practical update on the use of cetirizine in clinical practice.

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Published
2019-12-06
Info
Issue
Section
Reviews
Keywords:
Antihistamines, Cetirizine, Clinical practice, Histamine, H1 receptors
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How to Cite
Corsico, A. C., Leonardi, S., Licari, A., Marseglia, G., Miraglia del Giudice, M., Peroni, D. G., Salpietro, C., & Ciprandi, G. (2019). Focus on the cetirizine use in clinical practice: a reappraisal 30 years later. Multidisciplinary Respiratory Medicine, 14(1). https://doi.org/10.4081/mrm.2019.487