The use of exhaled nitric oxide and peak expiratory flow to demonstrate improved breathability and antimicrobial properties of novel face mask made with sustainable filter paper and Folium Plectranthii amboinicii oil: additional option for mask shortage during COVID-19 pandemic

  • Sy Duong-Quy | sduongquy.jfvp@gmail.com Medical-Biological Research Center, Lamdong Medical College, Da Lat city, Viet Nam.
  • Xuan Ngo-Minh Pham Ngoc Thach Medical University, Ho Chi Minh city, Viet Nam.
  • Trinh Tang-Le-Quynh Medical-Biological Research Center, Lamdong Medical College, Da Lat city, Viet Nam.
  • Tram Tang-Thi-Thao Medical-Biological Research Center, Lamdong Medical College, Da Lat city, Viet Nam.
  • Bao Nguyen-Quoc Medical-Biological Research Center, Lamdong Medical College, Da Lat city, Viet Nam.
  • Khiet Le-Quang Medical-Biological Research Center, Lamdong Medical College, Da Lat city, Viet Nam.
  • Dinh Tran-Thanh Medical-Biological Research Center, Lamdong Medical College, Da Lat city, Viet Nam.
  • Nhu Doan-Thi-Quynh Medical-Biological Research Center, Lamdong Medical College, Da Lat city, Viet Nam.
  • Ethan Canty Division of Immuno-Allergology, Hershey Medical Center, Penn State Medical College, Hershey, PA, United States. https://orcid.org/0000-0003-2711-7527
  • Toan Do Division of Immuno-Allergology, Hershey Medical Center, Penn State Medical College, Hershey, PA, United States. https://orcid.org/0000-0002-9098-4538
  • Timothy Craig Division of Immuno-Allergology, Hershey Medical Center, Penn State Medical College, Hershey, PA, United States.

Abstract

Background: Medical face masks are integral personal protective equipment against infectious airborne disease and become scarce during epidemic outbreaks such as COVID-19. A novel, sustainably manufactured face mask with antimicrobial and anti-inflammatory properties from oil of Folium Plectranthii amboinicii can be an effective alternative to internationally sold masks. Methods: This prospective, randomized study assigned subjects (n=67) to either conventional surgical face mask or Lamdong Medical College (LMC) face mask for three hours. Fractional concentration of nitric oxide in exhaled breath (FENO) and peak expiratory flow (PEF) was measured before and after mask use. Subjective reporting on respiratory symptoms was also analyzed. Masks were then incubated and analyzed for microorganism growth. Results: Subjects assigned the LMC mask had a lowered FENO (p<0.05) compared to conventional face masks after mask wearing. Subjects with LMC mask use reported higher comfortability (p<0.05), breathability (p<0.05), and lower allergy symptoms (p<0.05). The LMC mask has visually less microorganism growth in the cultured medium, measured by sterile ring radius. Conclusions: The LMC face mask is a renewably manufactured personal protective tool with antibacterial capacity that can serve as an effective alternative to internationally sold surgical face mask during shortage of mask due to COVID-19.

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Author Biography

Sy Duong-Quy, Medical-Biological Research Center, Lamdong Medical College, Da Lat city

Division of Immuno-Allergology, Hershey Medical Center, Penn State Medical College, Hershey, PA, USA; Pham Ngoc Thach Medical University, Ho Chi Minh city, Vietnam

Published
2020-06-01
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Original Research Articles
Keywords:
Filter paper mask, Folium Plectranthii amboinicii, Covid-19, pandemic, mask shortage
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How to Cite
Duong-Quy, S., Ngo-Minh, X., Tang-Le-Quynh, T., Tang-Thi-Thao, T., Nguyen-Quoc, B., Le-Quang, K., Tran-Thanh, D., Doan-Thi-Quynh, N., Canty, E., Do, T., & Craig, T. (2020). The use of exhaled nitric oxide and peak expiratory flow to demonstrate improved breathability and antimicrobial properties of novel face mask made with sustainable filter paper and <em>Folium Plectranthii amboinicii</em&gt; oil: additional option for mask shortage during COVID-19 pandemic. Multidisciplinary Respiratory Medicine, 15. https://doi.org/10.4081/mrm.2020.664