ISMAR-study presentation: in-hospital epidemiology and clinical management of respiratory and cardiac comorbidities in cardiac and respiratory disease units

Roberto Tramarin; Mario Polverino; Maurizio Volterrani; Bruna Girardi; Claudio Chimini; Nicolino Ambrosino; Fernando De Benedetto; Cesare Proto; and on behalf of the ISMAR Investigators

doi:10.4081/mrm.2014.406

ISMAR-study presentation: in-hospital epidemiology and clinical management of respiratory and cardiac comorbidities in cardiac and respiratory disease units

Authors

Roberto Tramarin Division of Cardiac Rehabilitation, IRCCS Policlinico San Donato - Care and Research Institute, San Donato Milanese, Milan
Mario Polverino High Specialty Provincial Pulmonologic Unit, “Scarlato” Hospital, Scafati (SA)
Maurizio Volterrani Division of Cardiac Rehabilitation, IRCCS San Raffaele Pisana - Care and Research Inst., Rome, Italy.
Bruna Girardi Division of Cardiac Rehabilitation, IRCCS Policlinico San Donato - Care and Research Institute, San Donato Milanese, (MI)
Claudio Chimini 4Division of Cardiology, Sant’Anna Hospital, Brescia
Nicolino Ambrosino Division of Pneumology, University Hospital Auxilium Vitae, Volterra
Fernando De Benedetto Division of Pneumology, Ss.Annunziata Hospital, Chieti
Cesare Proto Division of Cardiology, Sant’Anna Hospital, Brescia
and on behalf of the ISMAR Investigators the ISMAR Investigators

DOI: https://doi.org/10.4081/mrm.2014.406

Keywords:

Comorbidity, Diagnostic procedure, Epidemiology, In-hospital, Management, Treatment

Abstract

Background: Cardiovascular and respiratory diseases are leading causes of morbidity and their co-occurrence has important implications in mortality and other outcomes. Even the most recent guidelines do not reliably address clinical, prognostic, and therapeutic concerns due to the overlap of respiratory and cardiac diseases.

Study objectives and design: In order to evaluate in the reality of clinical practice the epidemiology and the reciprocal impact of cardio-pulmonary comorbidity on the clinical management, diagnostic workup and treatment, 1,500 cardiac and 1,500 respiratory inpatients, admitted in acute and rehabilitation units, will be enrolled in a multicenter, nationwide, prospective observational study. For this purpose, each center will enroll at least 50 consecutive patients. At discharge, data analysis will be aimed at the definition of cardiac and pulmonary inpatient comorbidity prevalence, demographic characteristics, length of hospital stay, and risk factors, taking into account also procedures, pharmacological and non-pharmacological treatment, and follow up in patients with cardio-respiratory comorbidity.

Conclusions: The purely observational design of the study aims to give new relevant information on the assessment and management of overlapping patients in real life clinical practice, and new insight for improvement and implementation of current guidelines on the management of individual diseases.