RP EBUS as a guide for transbronchial pulmonary biopsy in the diagnosis of organizing pneumonia

Gaetano Cicchitto; Mario Polverino; Antonio Capuozzo; Luigi Cacace; Antonietta Cavallera; Imma Mauro; Francesco Ferrigno; Francesca Polverino

doi:10.4081/mrm.2020.658

RP EBUS as a guide for transbronchial pulmonary biopsy in the diagnosis of organizing pneumonia

Authors

Gaetano Cicchitto Department of Pneumology and Endoscopic Unit, Ospedale “M. Scarlato”, Scafati (SA) https://orcid.org/0000-0002-2730-2303
Mario Polverino Department of Pneumology and Endoscopic Unit, Ospedale “M. Scarlato”, Scafati (SA) https://orcid.org/0000-0003-2856-2171
Antonio Capuozzo Department of Pneumology and Endoscopic Unit, Ospedale “M. Scarlato”, Scafati (SA) https://orcid.org/0000-0003-0006-8788
Luigi Cacace Division of Pathology, Ospedale “A. Tortora”, Pagani (SA)
Antonietta Cavallera Department of Radiology, Ospedale “M. Scarlato”, Scafati (SA)
Imma Mauro Department of Pneumology and Endoscopic Unit, Ospedale “M. Scarlato”, Scafati (SA)
Francesco Ferrigno Department of Pneumology and Endoscopic Unit, Ospedale “M. Scarlato”, Scafati (SA) https://orcid.org/0000-0002-1902-9714
Francesca Polverino Asthma and Airway Disease Center, University of Arizona, Tucson AZ, https://orcid.org/0000-0001-9686-5698

DOI: https://doi.org/10.4081/mrm.2020.658

Keywords:

Flexible bronchoscopy, organizing pneumonia, radial probe endobronchial ultrasonography, transbronchial pulmonary biopsy

Abstract

Diffuse parenchymal lung diseases (DPLDs) include a wide variety of manifestations characterized by different degrees of inflammation and fibrosis with various patterns of secondary lobule alterations, such that the diagnosis often requires histopathological confirmation in addition to clinical and radiological data. Radial probe endobronchial ultrasonography (RP EBUS) can be used as a guide for transbronchial pulmonary biopsy (TBPB) to obtain tissue samples, and thus can be a useful tool in the diagnostic management of peripheral pulmonary lesions. Organizing pneumonia (OP) is a particular type of DPLD characterized by lung inflammation and scarring that obstruct the small airways and air sacs of the lung. In this study, we describe how and when RP EBUS can be used to guide TBPB and significantly help in the diagnosis of OP.

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