Predictors of hypoxemia after general anesthesia in the early postoperative period in a hospital in Ethiopia: An observational study

Predictors of hypoxemia after general anesthesia in the early postoperative period in a hospital in Ethiopia: An observational study

Authors

  • Moges Gelaw Taye Department of Anesthesia, College of Health Sciences, Debre Tabor University, Debre Tabor https://orcid.org/0000-0002-9597-1613
  • Amelework Molla Department of Anesthesia, College of Health Sciences, Debre Tabor University, Debre Tabor
  • Diriba Teshome Department of Anesthesia, College of Health Sciences, Debre Tabor University, Debre Tabor
  • Metages Hunie Department of Anesthesia, College of Health Sciences, Debre Tabor University, Debre Tabor
  • Simegnew Kibret Department of Anesthesia, College of Health Sciences, Debre Tabor University, Debre Tabor
  • Yewlsew Fentie Department of Anesthesia, College of Health Sciences, Debre Tabor University, Debre Tabor
  • Netsanet Temesgen Department of Anesthesia, College of Health Sciences, Debre Tabor University, Debre Tabor
  • Melaku Tadege Engidaw Department of Public Health, College of Health Sciences, Debre Tabor University, Debre Tabor
  • Efrem Fenta Department of Anesthesia, College of Health Sciences, Debre Tabor University, Debre Tabor https://orcid.org/0000-0001-9709-8718

Keywords:

Postoperative hypoxemia, general anesthesia, Ethiopia

Abstract

Background: Early postoperative hypoxemia is a common problem after general anesthesia. The identification of factors associated with an increased occurrence of it might help healthcare professionals to hypoxemia risk patients, therefore this study aims to assess the incidence and factors associated with early postoperative hypoxemia among surgical procedures.
Methods: A prospective cohort study design was conducted from February 1, 2020 to June 30, 2020, on a total of 424 patients who underwent surgery under general anesthesia in Debre Tabor Comprehensive Specialized Hospital. The data was collected using a structured checklist. Bivariable and multivariable logistic regressions were used to check the association.
Results: The incidence of early postoperative hypoxemia was 45.8%. Patients having a BMI of 25-29.9 kg/m2 and BMI of 30-39.9 kg/m2, patients having a chronic disease, current smokers, SPO2 reading before induction of less than 95%, emergency surgery, and the absence of oxygen therapy during the period of transfer and/or in the post anesthesia care unit were significantly associated with an increased risk of hypoxemia in the early postoperative period.
Conclusions: The incidence of early postoperative hypoxemia was high in Debre Tabor Comprehensive Specialized Hospital. Obese patients, patients having a chronic disease, current smokers, and lower oxygen saturations before induction, emergency surgery, and the absence of oxygen therapy were the main predictors of an increased occurrence of early postoperative hypoxemia

References

Maity A, Saha D, Swaika S, Maulik SG, Choudhury B, Sutradhar M. Detection of hypoxia in the early postoperative period. Anesth Essays Res 2012;6:34.

Siddiqui N, Arzola C, Teresi J, Fox G, Guerina L, Friedman Z. Predictors of desaturation in the postoperative anesthesia care unit: an observational study. J Clin Anesthesia 2013;25:612-7.

Rosenberg J, Pedersen M, Gebuhr P, Kehlet H. Effect of oxygen therapy on late postoperative episodic and constant hypoxaemia. Br J Anaesth 1992;68:18-22.

Dalesio NM, McMichael DH, Benke JR, Owens S, Carson KA, Schwengel DA, et al. Are nocturnal hypoxemia and hypercapnia associated with desaturation immediately after adenotonsillectomy? Pediatr Anesth 2015;25-:778-85.

Vaughan RW, Engelhardt RC, Wise L. Postoperative hypoxemia in obese patients. Ann Surg 1974;180:877.

Jones J, Sapsford D, Wheatley R. Postoperative hypoxaemia: mechanisms and time course. Anaesthesia 1990;45:566-73.

Brown L, Purcell G, Traugott R F. Hypoxaemia during postoperative recovery using continuous pulse oximetry. Surv Anesthesiol 1991;35:288-9.

Uakritdathikarn T, Chongsuvivatwong V, Geater AF, Vasinanukorn M, Thinchana S, Klayna S. Perioperative desaturation and risk factors in general anesthesia. J Med Assoc Thai 2008;91:1020-9.

Karcz M, Papadakos PJ. Respiratory complications in the postanesthesia care unit: a review of pathophysiological mechanisms. Can J Respir Ther 2013;49:21.

Rosenberg J, Pedersen M, Gebuhr P, Kehlet H. Effect of oxygen therapy on late postoperative episodic and constant hypoxemia. Br J Anaesth 1992;68:18-22.

Habre W, Peták F. Perioperative use of oxygen: variabilities across age. Br J Anaesth 2014;113:ii26-ii36.

Kawanishi H, Inoue S, Kawaguchi M. A retrospective analysis of oxygen desaturation during acoustic respiratory rate monitoring in non-ICU patients following tracheal extubation after general anesthesia. Anesthesiol Res Pract 2017;2017:4203156.

Robson MJ, Alston PR, Deary IJ, Andrews PJ, Souter MJ, Yates S. Cognition after coronary artery surgery is not related to postoperative jugular bulb oxyhemoglobin desaturation. Anesth Analg 2000;91:1317-26.

Kieran S, Gorman C, Kirby A, Oyemwense N, Lander L, Schwartz M, et al. Risk factors for desaturation after tonsillectomy: analysis of 4092 consecutive pediatric cases. Laryngoscope 2013;123:2554-9.

Razlevice I, Rugyte DC, Strumylaite L, Macas A. Assessment of risk factors for cerebral oxygen desaturation during neonatal and infant general anesthesia: an observational, prospective study. BMC Anesthesiol 2016;16:1-8.

Meiklejohn B, Smith G, Elling A, Hindocha N. Arterial oxygen desaturation during postoperative transportation: the influence of operation site. Anaesthesia 1987;42:1313-5.

Jones J, Jordan C, Scudder C, Rocke D, Barrowcliffe M. Episodic postoperative oxygen desaturation: the value of added oxygen. J R Soc Med 1985;78:1019-22.

Vidhani K, Langham B. Obstructive sleep apnoea syndrome: is this an overlooked cause of desaturation in the immediate postoperative period? Br J Anaesth 1997;78:442-3.

Tadesse S, Fesaha G, Abebe A, Hailu B, Dejen W. Assessment of productive and reproductive performances of cross breed dairycows in Debre Tabor town. J Biol Agric Healthcare 2014;4:112-4.

Melesse DY, Denu ZA, Kassahun HG, Agegnehu AF. The incidence of early post-operative hypoxemia and its contributing factors among patients underwent operation under anesthesia at University of Gondar comprehensive and specialized referral hospital, Gondar, North West Ethiopia, 2018. A prospective observational study. Int J Surg Open 2020;22:38-46.

Labaste F, Silva S, Serin-Moulin L, Lefèvre E, Georges B, Conil J-M, et al. Predictors of desaturation during patient transport to the postoperative anesthesia care unit: an observational study. J Clin Anesth 2016;35:210-4.

Ramachandran SK, Thompson A, Pandit JJ, Devine S, Shanks AM. Retrospective observational evaluation of postoperative oxygen saturation levels and associated postoperative respiratory complications and hospital resource utilization. PloS One 2017;12:e0175408.

Ishikawa M, Sakamoto A. Postoperative desaturation and bradypnea after general anesthesia in non-ICU patients: a retrospective evaluation. J Clin Monit Comput 2020;34:81-7.

de Oliveira Filho GR, Garcia JHS, Ghellar MR, Nicolodi MA, Boso AL, Dal Mago AJ. [Factores asociados con la ocurrencia de hipoxemia en el período pós-anestésico inmediato].[Article in Portuguese]. Rev Bras Anestesiol 2001;51:185-95.

Wolde GD, Awol MA, Obsa MS, Wesene NG, Gemechu AD, Tadesse EN. Magnitude and associated factors of immediate postoperative hypoxemia among elective surgical procedures at Tikur Anbessa Specialized hospital, Addis Ababa, Ethiopia. J Anesth Clin Res 2018;9:5.

Kaushal A, Goyal P, Dhiraaj S, Agarwal A, Singh PK. Identification of various perioperative risk factors responsible for development of postoperative hypoxaemia. Turk J Anaesthesiol Reanim 2018;46:416.

<a href='https://it.freepik.com/foto/tecnologia'>Tecnologia foto creata da DCStudio - it.freepik.com</a>

Downloads

Published

01-12-2021

Issue

Section

Original Research Articles

How to Cite

1.
Taye MG, Molla A, Teshome D, Hunie M, Kibret S, Fentie Y, et al. Predictors of hypoxemia after general anesthesia in the early postoperative period in a hospital in Ethiopia: An observational study. Multidiscip Respir Med [Internet]. 2021 Dec. 1 [cited 2024 Nov. 20];16. Available from: https://mrmjournal.org/index.php/mrm/article/view/782