Kidney and lung in pathology: mechanisms and clinical implications
Keywords:
crosstalk, acute lung injury, acute kidney injury, chemokinesAbstract
There is a close, physiological, relationship between kidney and lung that begin in the fetal age, and is aimed to keep homeostatic balance in the body. From a pathological point of view, the kidneys could be damaged by inflammatory mediators or by immune-mediated factors linked to a primary lung disease or, conversely, it could be the kidney disease that causes lung damage. Non-immunological mechanisms are frequently involved in renal and pulmonary diseases, as observed in chronic conditions. This crosstalk has clinical and therapeutic consequences. This review aims to describe the pulmonary-renal link in physiology and in pathological conditions.
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