Preliminary study of assessing cognitive impairment in older patients with chronic obstructive pulmonary disease by using a cognitive functional assessment tool via a touchscreen personal computer

Preliminary study of assessing cognitive impairment in older patients with chronic obstructive pulmonary disease by using a cognitive functional assessment tool via a touchscreen personal computer

Authors

  • Masahiro Ogawa Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto https://orcid.org/0000-0003-0649-3822
  • Ayame Uchiumi Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto
  • Susumu Sato Department of Respiratory Care and Sleep Control Medicine and Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto
  • Yoko Hamakawa Department of Respiratory Medicine, Kitano Hospital, Osaka
  • Mizuki Kobashi Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto
  • Tomoki Aoyama Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto Kyoto; Department of Palliative Medicine, Kyoto University Hospital,
  • Hitoshi Tanimukai Department of Human Health Sciences, Graduate School of Medicine, Kyoto University; Department of Palliative Medicine, Kyoto University Hospital, Kyoto

Keywords:

COPD, cognitive impairment, elderly, assessment, computer, touchscreen

Abstract

Background: Unique cognitive impairments related to chronic obstructive pulmonary diseases (COPD) have been increasingly reported. Considering the dementia risk and medication management, older patients with COPD should be evaluated for cognitive impairment. This study aimed to examine whether specific cognitive impairments related to COPD could be detected by an assessment tool using a touchscreen personal computer (PC) in older patients with COPD.
Methods: This study included 28 older male patients with COPD and 30 healthy older male individuals. A touchscreen PC-based cognitive assessment application called CogEvo was used to assess and compare the cognitive function according to five domains: spatial cognition, orientation, working memory, executive function, and attention.
Results: Analysis of variance showed an interaction effect on the indices of cognitive function based on five domains between the two groups, indicating differences in the characteristics of cognitive function in such groups. Between-group comparisons as a subtest showed that attention, executive function, and working memory were significantly lower in the COPD group than in the healthy group.
Conclusion: CogEvo can detect specific cognitive impairments associated with COPD, suggesting that it can be potentially used as a screening tool for cognitive impairment in older patients with COPD.

Author Biographies

Masahiro Ogawa, Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto

Present address: Faculty of Rehabilitation, Kobe Gakuin University, Kobe, Japan

Ayame Uchiumi, Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto

Present address: Procurement Department, Hitachi High-Tech Corporation, Hitachinaka, Japan

Mizuki Kobashi, Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto

Present address: Department of Rehabilitation, Kyoto Hakuaikai Hospital, Kyoto, Japan

References

Ouellette DR, Lavoie KL. Recognition, diagnosis, and treatment of cognitive and psychiatric disorders in patients with COPD. Int J Chron Obstruct Pulmon Dis 2017;12 639-50.

Thakur N, Blanc PD, Julian LJ, Yelin EH, Katz PP, Sidney S, et al. COPD and cognitive impairment: the role of hypoxemia and oxygen therapy. Int J Chron Obstruct Pulmon Dis 2010;5:263-9.

Villeneuve S, Pepin V, Rahayel S, Bertrand JA, de Lorimier M, Rizk A, et al. Mild cognitive impairment in moderate to severe COPD: a preliminary study. Chest 2012;142:1516-23.

Yohannes AM, Chen W, Moga AM, Leroi I, Connolly MJ. Cognitive impairment in chronic obstructive pulmonary disease and chronic heart failure: A systematic review and meta-analysis of observational studies. J Am Med Dir Assoc 2017;18:451.e1-451.e11.

Singh B, Mielke MM, Parsaik AK, Cha RH, Robert RO, Scanlon PD, et al. A prospective of chronic obstructive pulmonary disease and the risk for mild cognitive impairment. JAMA Neurol 2014;71:581-8.

Cleutjens FA, Franssen FM, Spruit MA, Vanfleteren LE, Gijsen C, Dijkstra JB, et al. Domain-specific cognitive impairment in patients with COPD and control subjects. Int J Chron Obstruct Pulmon Dis 2017;12:1-11.

Dodd JW, Charlton RA, van den Broek MD, Jones PW. Cognitive dysfunction in patients hospitalized with acute exacerbation of COPD. Chest 2013;144:119-27.

Campman C, van Ranse D, Meijer JW, Sitskoorn M. Computerized screening for cognitive impairment in patients with COPD. Int J Chron Obstruct Pulmon Dis 2017;12:3075-83.

Turan O, Turan PA, Mirici A. Parameter affecting inhalation therapy adherence in elderly patients with chronic obstructive lung disease and asthma. Geriatr Gerontol Int 2017;17:999-1005.

Baird C, Lovell J, Johnson M, Shiell K, Ibrahim JE. The impact of cognitive impairment on self-management in chronic obstructive pulmonary disease: A systematic review. Respir Med 2017;129:130-9.

Yazar EE, Aydin S, Gunluoglu G, Kamat S, Gungen AC, Yildiz P. Clinical effects of cognitive impairment in patients with chronic obstructive pulmonary disease. Chron Respir Dis 2018;15:306-14.

Andrianopoulos V, Gloeckl R, Vogiatzis I, Kenn K. Cognitive impairment in COPD: should impairment cognitive evaluation be part of respiratory assessment? Breathe 2017;13:e1-e9.

Martinez Ch, Richardson CR, Han MK, Cigolle CT. Chronic obstructive pulmonary disease, cognitive impairment, and development of disability: the health and retirement study. Ann Am Thorac Soc 2014;11:1362-70.

Spannella F, Giulietti F, Cocci G, Landi L, Lombardi FE, Borioni E, et al. Acute exacerbation of chronic obstructive pulmonary disease in oldest adults: predictors of in-hospital mortality and need for post-acute care. J Am Med Dir Assoc 2019;20:893-8.

Ichii S, Nakamura T, Kawarabayashi T, Takatuma M, Ohgami T, Ihara K, et al. CogEvo, a cognitive function balancer, is a sensitive and easy psychiatric test battery for age-related cognitive decline. Geriatr Gerontol Int 2020;20:248-55.

Honda M, Hashimoto K, Miyamura K, Goto H, Abo M. Validity and reliability of a computerized cognitive assessment tool ‘Higher Brain Functional Balancer’ for healthy elderly people. Japan J Cognit Neurosci 2010;12:191-7.

Hashimoto K, Goto H, Abo M. Computerized assessment tool for healthy elderly persons as a predictor of cognitive function. Jikeikai Med J 2010;57:1-4.

Vogelmeier CF, Criner GJ, Martinez FJ, et al. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary. Eur Respir J 2017;49:1700214.

Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-98.

Nasreddine ZS, Phillips NA, Bedirian V, Charbonneau S, Whitehead V, Collin I, et al. The Montreal Cognitive Assessment, MoCA; A brief screening tool for mild cognitive impairment. J Am Geriatr Soc 2005;53:695-9.

Sugishita M. The cutoff point of MMSE-J; MMSE-J technical report #3. Nihon Bunka Kagakusha Co., Ltd. 2018. Accessed: November 11, 2021. Available from: https://www.nichibun.co.jp/documents/kensa/technicalreport/mmse_tech_3.pdf

Fujiwara Y, Suzuki A, Yasunaga M, Sugiyama Mika, Ijuin Mutsuo, Sakuma N, et al. Brief screening tool for mild cognitive impairment in order Japanese: Validation of the Japanese version of the Montreal Cognitive Assessment. Geritr Gerontol Int 2010;10:225-32.

Takechi H, Yoshino H. Usefulness of CogEvo, a computerized cognitive assessment and training tool, for distinguishing patients with mild Alzheimer’s disease and mild cognitive impairment from cognitively normal older people. Geriatr Gerontol Int 2021;21:192-6.

Allen SC, Zaman S. A comparison of the Turbohaler with a standard metered dose inhaler in elderly subjects with normal and impaired cognitive function. J Hong Kong Geriatr Soc 2000;10:75-7.

Fraser M, Pate M, Norkus EP, Whittington C. The role of cognitive impairment in the use of the Diskus inhaler. J Am Med Dir Assoc 2012;13:390-3.

Aquino G, Iuliano E, di Cagno A, Vardaro A, Fiorilli G, Moffa S, et al. Effects of combined training vs aerobic training on cognitive functions in COPD: a randomized controlled trial. Int J Chron Obstruct Pulmon Dis 2016;11:711-8.

Pereira ED, Viana CS, Taunay TC, Sales PU, Lima JWO, Holanda MA. Improvement of cognitive function after a three-month pulmonary rehabilitation program for COPD patients. Lung 2011;189:279-85.

Mei L, Wu S, Wang D, Li, H, Zhang H, Wang M. Epidemiology of dementia in elderly chronic obstructive pulmonary disease patients living in China’s northwestern high-elevation area. Med Sci Monit 2018;24:7742-9.

Negro RWD, Bonadiman L, Bricolo FP, Tognella S, Turco P. Cognitive dysfunction in severe chronic obstructive pulmonary disease (COPD) with or without Long-term Oxygen Therapy (LTOT). Multidiscip Respir Med 2015;10:17.

Karamanli H, Ilik F, Kayhan F, Pazarli AC. Assessment of cognitive impairment in long-term oxygen therapy-dependent COPD patients. Int J Chron Obstruct Pulmon Dis 2015;10: 2087-94.

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Published

01-02-2023

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Original Research Articles

How to Cite

1.
Ogawa M, Uchiumi A, Sato S, Hamakawa Y, Kobashi M, Aoyama T, et al. Preliminary study of assessing cognitive impairment in older patients with chronic obstructive pulmonary disease by using a cognitive functional assessment tool via a touchscreen personal computer. Multidiscip Respir Med [Internet]. 2023 Feb. 1 [cited 2024 Jul. 4];18(1). Available from: https://mrmjournal.org/index.php/mrm/article/view/892