Gorham-Stout disease and multiple cervical lymphangiomas: case report

Gorham-Stout disease and multiple cervical lymphangiomas: case report

Authors

  • Maria Alejandra Amezquita Fundacion Valle del Lili
  • Luz Fernanda Sua Fundacion Valle del Lili
  • Carlos Alejandro Garcia Fundacion Valle del Lili
  • Liliana Fernández-Trujillo Fundacion Valle del Lili https://orcid.org/0000-0003-0789-9154

Keywords:

Lymphangioma , Gorham-stout Disease , Pleural Effusion , Sirolimus , Case Report

Abstract

Introduction: Gorham-Stout disease is a rare condition characterized by extensive bone loss due to the proliferation of new vascular and lymphatic structures. It can occur in any bone and cause pathologic fractures with poor bone healing. Complications such as effusions and lymphangiomas can also develop. Gorham-Stout disease pathogenesis is still being studied, and treatment options are limited, but sirolimus has shown promise in stabilizing or reducing symptoms.
Case presentation: We present a case of a 19-year-old male with Gorham-Stout disease, multiple cervical lymphangiomas, and several thoracic complications successfully treated with sirolimus.
Conclusions: Rare lymphatic diseases should be considered as a potential cause in adult patients with bone involvement and multiple cystic lesions in the neck, axillary, or abdominal regions after excluding more common causes. The complexity of diagnosing Gorham-Stout disease should be emphasized.

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Published

16-10-2024

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Section

Case Reports

How to Cite

1.
Amezquita MA, Sua LF, Garcia CA, Fernández-Trujillo L. Gorham-Stout disease and multiple cervical lymphangiomas: case report. Multidiscip Respir Med [Internet]. 2024 Oct. 16 [cited 2025 Jan. 18];19(1). Available from: https://mrmjournal.org/index.php/mrm/article/view/957